私密直播全婐app免费大渔直播,国产av成人无码免费视频,男女同房做爰全过程高潮,国产精品自产拍在线观看

當前位置: 首頁 >> 產業發展 >> 正文

Polyhydroxyalkanoates in nanobiotechnology

時間:2004-10-27
關鍵詞:Polyhydroxyalkanoates nanobiotechnology 來源:International Symposium on Biological Polyesters ,Auguest 22-27, 2004

 

S. Y. Lee

 

Metabolic and Biomolecular Engineering National Research Laboratory, Department of Chemical and Biomolecular Engineering, BioProcess Engineering Research Center, Bioinformatics Research Center, and Center for Ultramicrochemical Process Systems, Department of BioSystems, Korea Advanced Institute of Science and Technology, Daejeon 305-701, Korea

 

Nanobiotechnology is a new discipline that fuses biological research and nanotechnological research in such areas as molecular self-assembly, spatial positioning, microconstruction and biocomposite fabrication, and offers exciting possibilities for the miniaturization of bioanalytical system. One of the important research topics is to develop a platform technology that allows studying biomolecular interactions on solid supports. Obviously, it is prerequisite to develop a method to immobilize biomolecules specifically and robustly on the desired regions of the solid supports while allowing efficient biomolecule-biomolecule interactions. In this sense, polyhydroxyalkanoates (PHAs) are attractive biomaterials for the fabrication of novel nano and/or micro-scaled structures and well-defined surfaces because of thermoplastic or elastomeric properties. We have developed a proprietary technique using the PHA depolymerase binding domain as a capture ligand for selective immobilization of any proteins and/or peptides onto the patterned or non-patterned surface of PHA. In one example, microcontact printing was employed to develop a well defined pattern of fusion proteins with 50 mm repeated stripes or circles on PHA. In another example, we developed a novel microbead-based assay system suitable for the analysis of protein-protein interactions. Direct contact printing of biomolecules onto the PHA chip could also be realized. Detailed results along with potential applications will be presented.

 

 

This work was supported by the KOSEF through the Center for Ultramicrochemical Process Systems, and also by the IMT-2000 project through the B-SAN.
Further support by LG Chemicals Chair Professorship is appreciated.

 

論文來源:International Symposium on Biological Polyesters ,Auguest 22-27, 2004

主站蜘蛛池模板: 云南省| 天镇县| 长宁县| 福建省| 宜宾县| 宁城县| 浙江省| 临沂市| 师宗县| 昌都县| 曲水县| 米林县| 个旧市| 洛隆县| 汕尾市| 宜城市| 广水市| 沂水县| 克什克腾旗| 库车县| 含山县| 凤城市| 康保县| 靖边县| 郑州市| 榆树市| 深水埗区| 竹北市| 开阳县| 通海县| 镇江市| 广平县| 大姚县| 福鼎市| 乌海市| 湘乡市| 大洼县| 长沙市| 台安县| 青川县| 天镇县|