Reversible photoswitching aggregation and dissolution of spiropyranfunctionalized copolymer and light-responsive FRET process
作者：Lei-Xiao Yu, Yang Liu, Si-Chong Chen *, Yue Guan, Yu-Zhong Wang*
關(guān)鍵字：RAFT polymerization; Spiropyran; Light-responsive; Self-assemble; Fluorescence resonance energy transfer
論文來源：期刊
具體來源：Chinese Chemical Letters
發(fā)表時間：2013年
Well-defined, reversibly light-responsive amphiphilic diblock copolymer grafted with spiropyran, was prepared by reversible addition–fragmentation chain transfer (RAFT) polymerization. The copolymer self-assembles into polymeric micelles in water and exhibits reversible dissolution and re-aggregation characteristics upon ultraviolet (UV) and visible (Vis)-light irradiation. The fluorescence response of spiropyran immobilized onto the copolymer was light switchable. When nitrobenzoxadiazolyl derivative (NBD) dyes are encapsulated into the core of the micelles, a reversible, light-responsive, dual-color fluorescence resonance energy transfer (FRET) system is constructed and processed, which is well regulated by alternatively UV/vis irradiation. We anticipate these photoswitchable and FRET lighting up nanoparticles will be useful in drug delivery and cell imaging or tracking synchronously.