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pH-Sensitive Vesicles Based on a Biocompatible Zwitterionic Diblock Copolymer
作者:Jianzhong Du, Yiqing Tang, Andrew L. Lewis, and Steven P. Armes
關鍵字:polymer vesicles, self-assembly
論文來源:期刊
具體來源:J. Am. Chem. Soc., 2005, 127 (51), pp 17982–17983
發表時間:2005年

Highly biocompatible pH-sensitive diblock copolymer vesicles were prepared from the self-assembly of a biocompatible zwitterionic copolymer, poly[2-(methacryloyloxy)ethyl phosphorylcholine-block-2-(diisopropylamino)ethyl methacrylate], PMPC-b-PDPA. Vesicle formation occurred spontaneously by adjusting the solution pH from pH 2 to above 6, with the hydrophobic PDPA chains forming the vesicle walls. Transmission electron microscopy (TEM), dynamic laser light scattering (DLS), and UV−visible absorption spectrophotometry were used to characterize these vesicles. Gold nanoparticle-decorated vesicles were also obtained by treating the vesicles with HAuCl4, followed by NaBH4.

http://pubs.acs.org/doi/abs/10.1021/ja056514l?prevSearch=%255Bauthor%253A%2Bjianzhong%2Bdu%255D&searchHistoryKey=

 

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