私密直播全婐app免费大渔直播,国产av成人无码免费视频,男女同房做爰全过程高潮,国产精品自产拍在线观看

相關(guān)鏈接
聯(lián)系方式
  • 通信地址:杭州下沙高教園2號(hào)大街928號(hào)
  • 郵編:310018
  • 電話:0571-86843527
  • 傳真:
  • Email:ghjiang_cn@zstu.edu.cn
當(dāng)前位置:> 首頁(yè) > 最新動(dòng)態(tài) > 正文
碩士研究生李培鑫等完成的研究論文被《International Journal of Biological Macromolecules》錄用!

由碩士研究生李培鑫等完成的研究論文“Fabrication of carboxymethyl cellulose/hyaluronic acid/polyvinylpyrrolidone composite pastes incorporation of minoxidil-loaded ferulic acid-derived lignin nanoparticles and valproic acid for treatment of androgenetic alopecia”被《International Journal of Biological Macromolecules(IF=8.20)》錄用!祝賀!!

Abstract: Androgenetic alopecia (AGA) is a transracial and cross-gender disease worldwide with a higher prevalence among young individuals. Traditional oral or subcutaneous injections are often used to treat AGA, however, they may cause severe side-effects and therefore effective treatments for AGA are currently lacking. In this work, to treat AGA, we developed a composite paste system based on minoxidil (MXD)-loaded nanoparticles and valproic acid (VPA) with the assistance of roller-microneedles (MNs). The matrix of composite paste systems is carboxymethyl cellulose (CMC), hyaluronic acid (HA) and polyvinylpyrrolidone (PVP). The roller-MNs can create microchannels in the skin to enhance drug transdermal efficiency. With the combined effects of the stimulation hair follicle (HF) regrowth by upregulating Wnt/beta-catenin of VPA and the mechanical microchannels induced by roller-MNs, the as-prepared composite paste systems successfully boost perifollicular vascularization, and activate hair follicle stem cells, thereby inducing notably faster hair regeneration at a lower administration frequency on AGA mouse model compared with minoxidil. This approach offers several benefits, including the avoidance of efficacy loss due to the liver’s first-pass effect associated with oral drug, reduction in the risk of infection from subcutaneous injection, and significant decrease in the side effects of lower-dose MXD.

主站蜘蛛池模板: 彩票| 枣庄市| 丰原市| 乌拉特后旗| 罗甸县| 南京市| 威海市| 太白县| 闵行区| 柘荣县| 遂昌县| 安岳县| 斗六市| 长汀县| 三明市| 海淀区| 安远县| 石渠县| 东台市| 星子县| 黄石市| 海盐县| 双鸭山市| 海伦市| 永德县| 肇州县| 隆德县| 介休市| 泗水县| 炎陵县| 通河县| 丰台区| 宜君县| 敖汉旗| 遂溪县| 太仓市| 于田县| 嘉峪关市| 江山市| 潜江市| 古蔺县|