作者：Shi, B. J.; He, Y. Y.;Zhang, P. P.; Wang, Y. L.; Yu, M. M.*;Zhang, H. Y. * Wei, L. H.; Li, Z. X.*
關鍵字：Fluorescent probe，1,8-naphthalimde，Hydrazine
論文來源：期刊
具體來源：Dyes Pigments, 2017, 152-159
發(fā)表時間：2017年
It is crucial to develop highly sensitive and selective probes toward hydrazine because it is a class of highly toxic and pollutant compound. Herein, using fracture of carbon carbon double bond and dissociation of amide by hydrazine, a novel off-on fluorescent probe was developed for hydrazine. The probe can quantitatively detect hydrazine in concentration range from 0 to 20 mM with the LOD of 140 nM. Further, it displayed excellent selectivity and anti-interference ability over many neutral molecules, metal ions, anions, and biological species. The ability to target lysosome and the response of hydrazine to this probe in a living cell was successfully tracked via fluorescence imaging。