私密直播全婐app免费大渔直播,国产av成人无码免费视频,男女同房做爰全过程高潮,国产精品自产拍在线观看

相關鏈接
聯系方式
  • 通信地址:哈爾濱,香坊區,林園路4號
  • 郵編:150040
  • 電話:0451-86392500
  • 傳真:
  • Email:mayingyi@hrbust.edu.cn
當前位置:> 首頁 > 論文著作 > 正文
A patterned porous polymer film for localized capture of insulin and glucose-responsive release
作者:Liang, Jing; Ma, Yingyi; Sims, Savannah等
關鍵字:porous film, insulin, glucose-responsive release
論文來源:期刊
具體來源:J. Mater. Chem. B
發表時間:2014年
A glucose-responsive, porous polymer film which can be used for controlled insulin release was fabricated. By mixing a polystyrene-dichloromethane solution containing didodecylamine with water, with thorough shaking, a reverse microemulsion was achieved. After spreading the microemulsion on aglass slide and evaporating the solvent, an ordered honeycomb-patterned film was produced, accompanied by an accumulation of didodecylamine within the inner surface of the cavities. The patterned cavities were further modified with poly(acrylic acid), 3-aminophenylboronic acid, and alginate so that they would entrap insulin aggregates. The insulin aggregates were prepared using a salting-out method and were incorporated into the cavities by an electrostatic interaction with the alginate. Under the stimulus of glucose, insulin aggregates were released from the cavities and further calculations demonstrated that there was a very high efficiency of release. In contrast, in an aqueous solution without glucose, almost no insulin was released from the cavities. This investigation demonstrates that it is feasible for porous polymer films, whose cavities act as a protein reservoir, to be used as a glucose-responsive insulin delivery vehicle, which may have potential as a controlled-release drug-delivery system for the treatment ofdiabetes.
主站蜘蛛池模板: 巧家县| 大城县| 栖霞市| 南漳县| 建平县| 防城港市| 宁城县| 汨罗市| 九寨沟县| 塔河县| 开封县| 合山市| 息烽县| 汨罗市| 长丰县| 丽水市| 东方市| 望奎县| 息烽县| 颍上县| 鹿邑县| 鹰潭市| 桓台县| 项城市| 乌兰察布市| 尼勒克县| 东宁县| 双牌县| 卓资县| 扎兰屯市| 无锡市| 互助| 乳源| 大关县| 崇明县| 资源县| 乐安县| 五原县| 宜章县| 孙吴县| 增城市|