Nano-hydroxyapatite Surfaces Grafted with Electroactive Aniline Tetramers for Bone-Tissue Engineering
作者：Yadong Liu, Haitao Cui, Xiuli Zhuang, Peibiao Zhang, Yi Cui, Xianhong Wang, Yen Wei, Xuesi Chen
關(guān)鍵字：Conducting polymer
論文來(lái)源：期刊
具體來(lái)源：Macromolecular Bioscience (Impact Factor: 3.74). 02/2013; DOI: 10.1002/mabi.201200345
發(fā)表時(shí)間：2013年
An electroactive amino/carboxyl-capped aniline tetramer (AT) is covalently grafted to the surface of hydroxyapatite (HA) nanoparticles to generate novel electroactive HA-AT nanoparticles. The amount of AT ranges from 16.5 to 34.0 wt% and is characterized by thermogravimetric analysis (TGA). The HA-AT nanoparticles are characterized by Fourier transform IR (FTIR) spectroscopy, X-ray photoelectron spectroscopy (XPS), X-ray diffraction, and scanning electron microscopy (SEM). For the excellent electroactivity of HA-AT, the mixture of HA-AT and PLA shows much better adhesion ability and proliferation ability than that of HA and a PLA matrix. At a 15 wt% AT grafting amount, the matrix shows the best biocompatibility.