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New chemosynthetic route to linear ε-poly-lysine.
來源:陶友華研究員個人網(wǎng)站 發(fā)布日期:2016-12-21
作者:TAO Youhua*, CHEN Xiaoyu, JIA Fan, WANG Shixue, XIAO Chunsheng, CUI Fengchao, LI Yunqi, BIAN Zheng,
關(guān)鍵字:ε-poly-lysine
論文來源:期刊
具體來源:Chemical Science
發(fā)表時間:2015年

ε-Poly-lysine ( ε-PL) is an uncommon cationic, naturally-occurring homopolymer produced by the fermentation process. Due to its significant antimicrobial activity and nontoxicity to humans, ε-PL is now industrially produced as an additive, e.g. for food and cosmetics. However, the biosynthetic route can only make polymers with a molecular weight of about 3 kDa. Here, we report a new chemical strategy based on ring-opening polymerization (ROP) to obtain ε-PL from lysine.


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