New chemosynthetic route to linear ε-poly-lysine.
作者：TAO Youhua*, CHEN Xiaoyu, JIA Fan, WANG Shixue, XIAO Chunsheng, CUI Fengchao, LI Yunqi, BIAN Zheng,
關(guān)鍵字：ε-poly-lysine
論文來源：期刊
具體來源：Chemical Science
發(fā)表時間：2015年
ε-Poly-lysine ( ε-PL) is an uncommon cationic, naturally-occurring homopolymer produced by the fermentation process. Due to its significant antimicrobial activity and nontoxicity to humans, ε-PL is now industrially produced as an additive, e.g. for food and cosmetics. However, the biosynthetic route can only make polymers with a molecular weight of about 3 kDa. Here, we report a new chemical strategy based on ring-opening polymerization (ROP) to obtain ε-PL from lysine.