inventor/creator：楊 光，王剛，劉筆鋒，史續(xù)典，陳旭峰
Paten number/application number：ZL 200810047875.1
application/authorized announcemen date：2011-3-24
brief introduction：
本發(fā)明提供了一種通過(guò)微流控芯片制備圖案化纖維素的方法，按照以下步驟進(jìn)行：（1）依據(jù)預(yù)定圖案制作陽(yáng)膜；（2）制備與陽(yáng)膜圖案相匹配的聚二甲基硅氧烷(PDMS)模塊；（3）在PDMS模塊上打孔，將潔凈的載玻片壓緊于PDMS模塊有圖案的一面，形成微流控芯片，其中PDMS模塊上的圖案化管道通過(guò)孔與外界相連通；（4）在兩儲(chǔ)液槽中裝入細(xì)菌培養(yǎng)液，利用導(dǎo)管將微流控芯片的圖案化管道分別與兩儲(chǔ)液槽連通，調(diào)節(jié)兩儲(chǔ)液槽之間的液面差控制圖案化管道內(nèi)的液體流速，其液面差為1-20cm，培養(yǎng)5-20天，揭開(kāi)PDMS模塊，得到圖案化纖維素。采用本發(fā)明制得的細(xì)菌纖維素材料具有微觀的有序性和宏觀的圖案性，并兼有生物相容性和生態(tài)相容性，是理想的環(huán)境友好材料。
ABSTRACT:
NOVELTY - Patterning cellulose is prepared by perforating polydimethyl silicone (PDMS) module matching with the anode film patterns; placing bacterial culture solution to liquid tanks and culturing 5-20 days; and removing the PDMS module to obtain the patterning cellulose. The PDMS is perforated by compressing a clean glass slide on one surface of the PDMS module having the patterns to form the microfluidic chip.
USE - Method for preparing patterning cellulose (claimed).
ADVANTAGE - The prepared bacteria cellulose material comprises microcosmic sequence and macroscopic patterning performance, and biocompatibility and ecology compatibility; and is perfect environment-friendly material.
