私密直播全婐app免费大渔直播,国产av成人无码免费视频,男女同房做爰全过程高潮,国产精品自产拍在线观看

當前位置:> 首頁 > 論文著作 > 正文
Polystyrene N,O-Diacyl-N-sulfonyl Hydroxyamine. A New Double-Acyl Transfer Reagent for synthesis of the Amide Library
作者:Shufeng Li, Xinlin Yang, Wenqiang Huang*
關鍵字:polystyrene N-hydroxyl sulfonamide; polystyrene N,O-diacyl sulfonyl hydroxamate; acyl
論文來源:期刊
具體來源:Chin. J. Org. Chem,25 (1), 59-64 (2005).
發表時間:2005年
A new double-acyl transfer reagent, polystyrene N,O-diacyl-N-sulfonyl hydroxylamine resin 3,
was prepared and used in solution-phase synthesis of an amide library. Polystyrene N-hydroxyl sulfonyl amide resin 1 reacted with acid chloride 2 to form polystyrene N,O-diacyl sulfonyl hydroxamate 3, which was cleaved by amine 4 to form amide 5. The results showed that the double p-nitrobenzoyl resin 3a possessed the highest activity. Cleavage of double-acylated resin 3 by aliphatic amines gave the higher amide yields than by aromatic amines. In this way, a library with 24 amides was synthesized. When double-acylated resin
3 was cleaved by the reagent containing both amino and hydroxyl groups, only amino group was selectively acylated but the hydroxyl group remained unacylated. The reusability of resin 3a was also studied.
主站蜘蛛池模板: 深州市| 吐鲁番市| 临洮县| 克拉玛依市| 河间市| 泽普县| 汤原县| 铜梁县| 阿尔山市| 鸡西市| 长泰县| 偃师市| 班玛县| 黄大仙区| 东丽区| 隆化县| 前郭尔| 永宁县| 子洲县| 琼中| 仁怀市| 奉节县| 江都市| 卢龙县| 玉门市| 惠州市| 化州市| 象山县| 阿荣旗| 碌曲县| 嘉善县| 巴青县| 荣成市| 武川县| 新疆| 威信县| 浠水县| 同江市| 蓬溪县| 雷波县| 凌源市|