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High-efficiency loading in small mesopores (2–3 nm) forming a matrix type controlled drug delivery nanosystem
writer：Fang Liu, Hongwu Zhang,Qingyun Cao,Wuyi Zhou*, etal.
keywords：Mesoprous silica; Controlled drug delivery nanosystem; High-efficiency loading
source：期刊
specific source：RSC advances, 2014, 4, 8918-8921
Issue time：2014年
Herein a high-efficiency controlled release nanosystem for fluoroquinolonehydrochlorides was established by a characteristicvacuum-recrystal loaded process based on small pore mesoporousMCM-41. The system exhibited great drug loading capacity (62.31%),matrix type sustained-release behavior (5 days) and excellent biocompatibility in vitro.