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Current Location :> Home > Publications > Text
Molecular Self-Assembly of A Homopolymer: An Alternative to Fabricate Drug Delivery Platform for Cancer Therapy
writer:Liu, J.Y.; Huang, W.*; Pang, Y.; Huang, P.; Zhu, X.Y.; Zhou, Y. F.; Yan, D.Y.*
keywords:antitumor agents, drug delivery, polymers, redox chemistry, self-assembly
source:期刊
specific source:Angew. Chem. Int. Ed. 2011, 50, 9162. http://onlinelibrary.wiley.com/doi/10.1002/anie.201102280
Issue time:2011年


The best of both worlds: A novel amphiphilic homopolymer synthesized from a monomer consisting of a hydrophobic group (see picture, red) and a hydrophilic moiety (green) self-assembles in aqueous solution. The resulting micelles have a multi-core/shell structure and exhibit smart redox-responsive properties, thus providing a favorable drug delivery platform for cancer therapy.