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Multicompartment micelles (MCPs), comprising

sequences of repeated elemental discoid parts connected by

fasciculus, were formed by self-assembly of polystyrene-blockpoly(

2-vinyl pyridine)-block-poly(ethylene oxide). Using an

electrostatic field, the MCPs can be disassembled through

consequent release of small spherical micelles. During this

disassembly process, release of loaded species can be achieved

from the micelles in chronological order. Two location-selected

cargos (mitoxantrone (MTNT) and fluorescein isothiocyanate

(FITC)) in the outer and inner compartments of the micelles

can be released in chronological order. Under the applied

electrostatic field (intensity: 16 kVcm1), the loaded MTNT

was rapidly released with more than 80% release, whereas the

loaded FITC was slowly released with less than 20%release in

12 h. At a later stage (after more than 12 h), the loaded MTNT

was slowly released with less than 20% release, while the

loaded FITC was rapidly released with more than 80%release